Juxtapositions: Company Building in 2026

Building in 2026 will require organizations to operate inside constant tension and get stronger because of it. Our 2026 Juxtapositions outline the structural dynamics reshaping company building across capital markets, AI transformation, ecosystem partnerships, tech-enabled services, and regulation.

How AI is Re-Industrializing the Economy

Where Web 1.0 wired the economy and Web 2.0 layered software on top of it, the AI era is rebuilding industries from the inside out by embedding intelligence directly into machines, workforces, and physical systems. This is more than another app cycle. It’s an (industrial) revolution.

Juxtapose + General Catalyst - Inspiring the Next Generation of Healthcare Building

Juxtapose and General Catalyst partnered to host an event bringing together nearly 100 healthcare leaders – ranging from investors and board advisors to founders and operators, including engineers, product leaders, and growth executives – to dive into what building healthcare companies from the ground up will look like in an increasingly AI-powered world.

Juxtapositions: A New Podcast on Change, Leadership, and What Comes Next

Juxtapositions is a new series of conversations where members of our Concept Development, User Research & Design, and Talent team get to sit down with friends and business leaders — from CEOs to investors, operators to founders — who’ve navigated major transitions and unpack how they managed change, what they learned, and what advice they’d give others doing the same.

From Insight to Impact: Why User Research Shapes Every Juxtapose Company

As the creators and stewards of our portfolio companies, our entire team works to shape our businesses' futures by turning early user insights into products and experiences that are differentiated, delightful, and sticky. This “de-risking” work at the heart of Juxtapose’s creation-oriented investment philosophy is led by the User Research & Design team.

Being an Investor-Builder - And What it Means to Co-Build with Juxtapose

Today's founders don’t want passive investors. They want someone who can help translate their vision into business momentum. That’s where Juxtapose strives to go beyond the role of investor and become a true co-builder.

CEO Spotlight: Natalie Lemke, CEO of Rux

Juxtapose is partnering with Natalie Lemke to build ERP software designed for operationally-intense sectors like specialty manufacturing, construction, and equipment rental.

Inception Point: Attribution in Healthcare - Who’s Actually Responsible for Patient Outcomes?

While many PCPs already participate in Value-Based Care, fewer than 5% of specialists are meaningfully involved in alternative payment models today. Without solving attribution, we won’t be able to scale new care models for specialists or get the right patient into the right model at the right time (let alone pay for it accurately).